Other name(s):

a-amino-isovaleric acid

Unsubstantiated claims

Please note that this section reports on claims that have NOT yet been substantiated through scientific studies.

Valine may help treat malnutrition associated with drug addiction.

Recommended intake

Amino acids (AAs) are available as individual AAs or in proprietary AA combinations, as well as part of multi-vitamin formulas, proteins, and food supplements. The forms include tablets, fluids, and powders. However, adequate protein in the diet should provide a sufficient source of all amino acids.

Valine supplements should be taken together with leucine and isoleucine.

There are no conditions that increase the requirements for valine.

Side effects, toxicity, and interactions

The use of a single amino acid supplement may lead to a negative nitrogen balance, decreasing metabolic efficiency and increasing the workload in the kidneys. In children, taking single amino acid supplements may also harmfully affect growth parameters.

Always avoid taking individual amino acids in high dosage for prolonged periods.

Women who are pregnant or breastfeeding should not use valine supplements.

Individuals with maple syrup urine disease (MSUD), a rare inherited disorder, should also avoid supplemental use of valine.

Additional information

Click here for a list of reputable websites with general information on nutrition.