Epstein Barr Virus EBV Quantitative
 
 

Epstein-Barr Virus (EBV) Quantitative

Order name:
EBV PCR Quant

Specimen Requirements:
EDTA Peripheral blood, EDTA plasma, CSF

Minimum volume:
0.5mL

Storage and stability information:
Peripheral blood (Refrigerated, 1 week), Plasma (Refrigerated or frozen at -20°C, 1 week), CSF (Refrigerated or frozen at -20°, 1 week)

Test performed:
Once per week

Methodology:
Real-time Polymerase Chain Reaction (PCR)

Reference Range:
EBV DNA not detected

Linear range:
500 – 9,850,000 copies/mL

Limit of detection:
246 copies/mL in plasma and CSF, 500 copies/mL in whole blood

CPT code:
87497

Clinical significance:
Many people become infected with EBV in childhood. EBV infections in children usually do not cause symptoms, or the symptoms are not distinguishable from other mild, brief childhood illnesses. People who get symptoms from EBV infection, usually teenagers or adults, get better in 2 to 4 weeks. However some people feel fatigued for as long as several months. After an EBV infection, the virus becomes latent in the body. In some cases, the virus may reactivate. This does not always cause disease but people with compromised immune systems are more likely to develop serious symptoms