BK Virus Quantitative

BK Virus Quantitative

Order name:

Specimen Requirements:
EDTA plasma, urine

Minimum volume:

Storage and stability information:
Plasma (Refrigerated or frozen at -20°C, 1 week), Urine (Refrigerated, 72 hours)

Test performed:
Once per week

Real-time Polymerase Chain Reaction (PCR)

Reference Range:
BK virus DNA not detected

Linear range:
500 – 5,000,000 copies/mL

Limit of detection:
250 copies/mL in plasma, 500 copies/mL in urine

CPT code:

Clinical significance:
BK virus (BKV) is a double-stranded DNA virus and a member of the polyomavirus family. The virus is ubiquitous, having a worldwide seropositivity around 75%, and generally has very mild pathogenicity in healthy individuals.  BKV establishes lifelong latency in the urinary epithelium with often no debilitating effects. However BKV can cause clinical disease in immunocompromised patients.